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Major symptoms associated with hypersensitivity1
- May lead to misdiagnosis of hypersensitivity as respiratory disease (pneumonia, bronchitis, pharyngitis), or gastroenteritis.
- Worsen with continued therapy and can be life-threatening.
- Usually resolve upon discontinuation of abacavir.
Symptoms reported with a frequency ≥10% (n=1803)1
Hover over the symptoms bars for the exact figures.
Physical and laboratory findings1
|Physical findings||Possible laboratory abnormalities|
|Lymphadenopathy||Haematological: lymphopaenia and thrombocytopaenia|
|Mucous membrane lesions
|Chest x-ray normal or diffuse bilateral or lobular infiltrates|
|Elevated liver enzymes (AST/ALT)|
|Increased serum creatinine and creatinine phosphokinase|